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Freeze-Drying Options
Posted: Wednesday, March 1, 2017 12:00:00 AM
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Freeze-drying is a dehydration process typically used to preserve perishable material or make it more convenient to transport. The process involves freezing a substance, reducing the surrounding pressure, and adding enough heat to allow the frozen water in the material to sublimate, or change directly from the solid to gas state. Properly sealed freeze-dried substances can be stored at room temperature for years without spoiling. How is freeze-drying often used by pharmaceutical companies? More...
Posted: Thursday, March 2, 2017 12:35:44 PM

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Pharmaceutical Freeze Drying

The freeze drying process has important applications in the pharmaceutical and biotechnology industries, and pharmaceutical freeze drying is now a standard process used to stabilise, store or increase the shelf life of drug products and other biologicals.

Pharmaceutical Freeze Drying Process

Freeze drying pharmaceuticals uses a process called lyophilization to lower the temperature of the product to below freezing, and then a high-pressure vacuum is applied to extract the water in the form of vapour. The vapour collects on a condenser, turns back to ice and is removed. Finally, a gradual temperature rise extracts all remaining 'bound' moisture from the product. This process retains the physical structure and preserves the material for storage or transport.

Advantages of Freeze Drying Pharmaceuticals

With freeze drying, delicate, unstable or heat-sensitive drugs and biologicals can be dried at low temperatures without damaging their physical structure. Freeze-dried products can be reconstituted quickly and easily, which is particularly valuable in the case of emergency vaccines and antibodies, which need to be administered as quickly as possible.
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